Custom Enzymes and Inhibitors
Selleck Chemical LLC Everolimus (RAD001) 25mg 159351-69-6
Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Biochain Institute Inc Placenta Ribonuclease Inhibitor, 5000 units/PK
BioChain offers the most used enzymes in molecular biology and biochemistry, such as DNase I, RNase A, with premium quality and at the most competitive price.
Medchemexpress LLC NAE-IN-M22 25mg | 864420-54-2 | 363.32 g/mol | C20H24Cl2N2 | 25 MG
A potent, selective, reversible inhibitor of the NEDD8 activating enzyme (NAE) with demonstrated antiproliferative and proapoptotic activity in cancer cell lines and reported in vivo tumor growth inhibition. Supplied as a white to off-white solid with high purity and high solubility in DMSO, it is available in multiple pack sizes and solution formats for research use.
- Potent, selective, reversible NAE inhibition.
- Demonstrated antiproliferative and proapoptotic activity in cells.
- Effective in vivo tumor growth inhibition reported.
- High purity solid with white to off-white appearance.
- High solubility in DMSO and multiple stock concentration options.
Medchemexpress LLC CCI-006 10mg | 292053-42-0 | 10 MG
Methyl 2-cyano-3-(5-(4-sulfamoylphenyl)furan-2-yl)acrylate is a small-molecule mitochondrial respiration inhibitor that functions as a chemosensitizer in MLL-rearranged leukemia research; supplied as a light-yellow solid with high purity for preclinical laboratory use.
- High purity suitable for research applications.
- Molecular weight 332.33 g/mol; formula C15H12N2O5S.
- Stable as powder at -20 °C for up to 3 years; in solvent store at -80 °C for up to 6 months.
- Available in small pack sizes appropriate for in vitro studies.
- Acts as a mitochondrial respiration inhibitor and chemosensitizer in MLL-r leukemia models.